TMEM43-S358L MUTATION ENHANCES NF-κB-TGFβ SIGNAL CASCADE IN ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA/CARDIOMYOPATHY

TMEM43-S358L mutation enhances NF-κB-TGFβ signal cascade in arrhythmogenic right ventricular dysplasia/cardiomyopathy

Abstract Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is a genetic cardiac muscle disease that accounts for approximately 30% sudden cardiac death in young adults.The Ser358Leu mutation of transmembrane protein 43 (TMEM43) was commonly identified in the patients of highly lethal and fully penetrant ARVD subtype, ARVD5.Here, we

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High Power Output Augmented Vertical Axis Wind Turbine

Nowadays, wind energy is one of the most cost-effective and environmentally friendly energies in high demand due to shortages in fossil fuels and the necessity to reduce global carbon footprint.One of the main goals of wind turbine development is to increase the power output of the turbine either by increasing the turbine blade swept Universal Lapt

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Contraceptive utilization and associated factors among polygamous and monogamous women in Worebabo Woreda, South Wollo Zone, Ethiopia: a comparative cross sectional study

Abstract Background In Ethiopia high population growth and unintended pregnancies are posing pressures where the economy is incapable of holding overpopulation.Despite this problem, utilization of modern contraception is low in rural areas of the country, especially in the areas where polygamy is common.Therefore, this study was conducted to assess

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